Anastrozole Patient Handout

What is Anastrozole?

Anastrozole is a medication used to treat hormone receptor-positive breast cancer in postmenopausal women. It belongs to a class of drugs called aromatase inhibitors, which work by reducing the amount of estrogen in the body. This helps slow or stop the growth of estrogen-dependent breast cancer cells.

How to Take Anastrozole

• Dosing: The usual dose is 1 mg taken orally once daily. Your healthcare provider will determine the appropriate duration of treatment.
• Take Anastrozole at the same time each day, with or without food.
• Swallow the tablet whole with water. Do not crush or chew the tablet.

Possible Side Effects

Anastrozole can cause side effects. Common ones include:

• Hot flashes
• Joint or muscle pain
• Fatigue
• Nausea
• Headaches
• Vaginal dryness
• Hair thinning

Less common but serious side effects:

• Bone thinning or osteoporosis, increasing the risk of fractures
• Elevated cholesterol levels
• Liver function changes

If you experience severe or unusual symptoms, contact your healthcare provider immediately.

Pregnancy Precautions

• Anastrozole is intended for postmenopausal women and should not be used during pregnancy.
• If you are of childbearing potential, use effective contraception during treatment and for at least 3 weeks after stopping the medication.
• If you think you are pregnant while taking Anastrozole, contact your doctor immediately.

Storage

• Store Anastrozole at room temperature (68°F to 77°F or 20°C to 25°C).
• Keep the medication in its original container, away from moisture and light.
• Keep out of reach of children.

What to Do If You Miss a Dose

• If you miss a dose, take it as soon as you remember.
• If it is close to the time for your next dose, skip the missed dose. Do not take two doses at the same time.

Before Taking Anastrozole, Tell Your Doctor If:

• You have a history of osteoporosis or bone fractures.
• You have high cholesterol or liver problems.
• You are pregnant, planning to become pregnant, or breastfeeding.
• You are taking any other medications, vitamins, or herbal supplements.

When to Contact Your Physician

• Immediately:
  • If you experience severe bone pain or fractures.
  • If you notice symptoms of liver problems (e.g., yellowing of the skin or eyes, dark urine).
  • If you experience severe allergic reactions, such as rash, itching, or swelling.
• As soon as possible:
  • If you experience persistent joint or muscle pain.
  • If you notice unusual or severe side effects.

Disclaimer: This handout is intended for educational purposes only and does not replace professional medical advice. Always follow the guidance of your healthcare provider regarding your medications and health conditions.