Carboplatin

What is Carboplatin?

Carboplatin is a chemotherapy medication used to treat various types of cancer, including ovarian, lung, head and neck, and other solid tumors. It works by damaging the DNA of cancer cells, preventing them from dividing and growing. This medication is administered by a healthcare professional, typically as an intravenous (IV) infusion.

How is Carboplatin Administered?

• Carboplatin is given as an IV infusion, usually in a hospital or clinic setting.
• The dose and frequency depend on your type of cancer, body weight, kidney function, and treatment plan prescribed by your oncologist.
• You may receive pre-medications to help prevent side effects such as nausea.

Possible Side Effects

Carboplatin can cause side effects. Common ones include:

• Nausea and vomiting
• Fatigue
• Temporary hair loss
• Low blood cell counts (white cells, red cells, and platelets), increasing the risk of infections, anemia, or bleeding
• Changes in taste
• Weakness

Less common but serious side effects:

• Allergic reactions, including rash, itching, or difficulty breathing
• Kidney function changes
• Hearing loss or ringing in the ears (ototoxicity)
• Severe infections due to low white blood cell counts

If you experience severe or unusual symptoms, contact your healthcare provider immediately.

Precautions Before Starting Carboplatin

• Inform your doctor if you have a history of:
  • Kidney problems
  • Hearing loss
  • Blood disorders
  • Allergies to platinum-containing medications (e.g., cisplatin)
• Discuss any other medications, vitamins, or herbal supplements you are taking.
• Use effective contraception during treatment and for a period afterward, as Carboplatin can harm an unborn baby.
• Avoid live vaccines during treatment.

Managing Side Effects

• Nausea and vomiting: Anti-nausea medications will often be prescribed. Eat small, bland meals if needed.
• Fatigue: Rest as needed and maintain a balanced diet.
• Low blood counts: Follow your doctor’s advice to prevent infections, such as frequent handwashing and avoiding sick individuals.
• Hearing changes: Inform your healthcare provider if you notice hearing loss or ringing in your ears.

When to Contact Your Physician

• Immediately:
  • If you experience fever, chills, or signs of infection.
  • If you notice unusual bruising or bleeding.
  • If you develop difficulty breathing, swelling, or severe rash.
• As soon as possible:
  • If you notice changes in urination or swelling in the legs.
  • If you experience persistent nausea or vomiting.
  • If you notice hearing loss or ringing in the ears.

Storage and Handling

• Carboplatin is administered by healthcare professionals and is not stored at home.

Disclaimer: This handout is intended for educational purposes only and does not replace professional medical advice. Always follow the guidance of your healthcare provider regarding your medications and health conditions.