Docetaxel for Prostate Adenocarcinoma

Cycle	Day	Treatment	Common Side Effects
Cycle 1	Day 1	Docetaxel 75 mg/m² IV infusion + Prednisone 5 mg orally twice daily	Neutropenia, fatigue, nausea, diarrhea, fluid retention
Cycle 2	Day 22	Docetaxel 75 mg/m² IV infusion + Prednisone 5 mg orally twice daily	Neutropenia, neuropathy, alopecia, anorexia
Cycle 3	Day 43	Docetaxel 75 mg/m² IV infusion + Prednisone 5 mg orally twice daily	Febrile neutropenia, infection, nail changes, stomatitis
Cycle 4	Day 64	Docetaxel 75 mg/m² IV infusion + Prednisone 5 mg orally twice daily	Anemia, peripheral edema, taste disturbance, vomiting
Cycle 5	Day 85	Docetaxel 75 mg/m² IV infusion + Prednisone 5 mg orally twice daily	Dyspnea, rash, desquamation, arthralgia
Cycle 6	Day 106	Docetaxel 75 mg/m² IV infusion + Prednisone 5 mg orally twice daily	Sensory neuropathy, motor neuropathy, tearing, cardiac issues

Notes:

• Docetaxel Administration: Administered once every three weeks (21-day cycle) for up to six cycles.
• Prednisone: Taken orally twice daily throughout the treatment to help manage side effects and improve efficacy.
• Monitoring: Regular monitoring for hematologic and non-hematologic toxicities is essential. Dose adjustments may be necessary based on the severity of side effects.
• Premedication: Patients may receive corticosteroids before docetaxel infusion to reduce the risk of allergic reactions and fluid retention.

This schedule provides a structured approach to administering docetaxel while highlighting potential side effects that require monitoring and management.